|
Symbol Name ID |
Il12a
interleukin 12a MGI:96539 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgM level |
Splenomegaly |
Celiac disease |
Gastrointestinal inflammation |
Hepatitis |
Subacute progressive viral hepatitis |
Autoimmunity |
Antimitochondrial antibody positivity |
Antinuclear antibody positivity |
Recurrent fungal infections |
Onychomycosis |
| Disease(s) Associated with IL12A | ||||||||||||
| hepatocellular carcinoma | ||||||||||||
| primary biliary cholangitis |
| Mouse Phenotypes | immune system phenotype |
abnormal NK cell physiology |
impaired natural killer cell mediated cytotoxicity |
abnormal CD4-positive, alpha-beta T cell physiology |
decreased circulating interferon-gamma level |
decreased circulating interleukin-12 level |
decreased susceptibility to type IV hypersensitivity reaction |
increased susceptibility to parasitic infection |
increased susceptibility to Herpesvirales infection |
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| Availability | Mouse Genotype | |||||||||
| Il12am1Btlr/Il12am1Btlr | ||||||||||
| Il12atm1Cab/Il12atm1Cab | ||||||||||
| Il12atm1Jm/Il12atm1Jm | * | |||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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